Claim THR-04

Claim THR-04

In chronically lonely people, white blood cells show a shifted pattern of gene activity: inflammation-related genes turned up, antiviral and antibody-related genes turned down.Known (claim THR-04: sources and how to dispute it)Ch. 13, Ch. 14 and Prologue

Its mark
Known. Supported by robust, replicated evidence and accepted by the relevant scientific mainstream. Solid ground.
Basis
finding. A claim about how the world is, answerable to evidence.
How it was checked
Corrected from the manuscript

Sources

  1. Cole, S. W., Hawkley, L. C., Arevalo, J. M., Sung, C. Y., Rose, R. M., & Cacioppo, J. T. (2007). Social regulation of gene expression in human leukocytes. Genome Biology, 8(9), R189. DOI 10.1186/gb-2007-8-9-r189
  2. Alwis, H. The Cathedral: Detailed Notes on the Text (manuscript, March 2026 version in the World Systems project).

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